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AI·OpenAI released GPT-5.6 in three tiers—Sol (flagship), Terra, and Luna—boosting benchmarks in Agent's Last Exam (56.3 score), math, coding, security, and research while slashing token costs and adding Max/Ultra reasoning modes.

36氪 AI·36kr.com··3.0Releaseopenaigptllm

AI·OpenAI folds Codex into the new ChatGPT desktop app as Work mode, shifting focus to usage-based billing and water-meter-style pricing for AI agents, effectively 'killing' the old standalone Codex product.

36氪 AI·36kr.com··2.8Releaseopenaicodexgpt

Current computational approaches for drug design typically focus on generating molecules conditioned on specific targets or general molecular properties, often neglecting the influence of disease context on target behavior and therapeutic outcomes. To address this gap, we introduce DrugGen-2, a novel generative model that designs small molecules conditioned on both disease ontology and target protein sequences. DrugGen-2 was developed by fine-tuning a pre-trained GPT-2 model on a curated datase…

HuggingFace Daily Papers·huggingface.co··0.6paper